3rd Generation vs. Taiwan’s 4th Generation IVF success rate comparison

Since the first successful IVF birth in 1978, the technology has advanced significantly. Key innovations like ICSI in the 1990s (2nd generation) and PGT-A (3rd generation) have greatly improved success rates, which now range from 30% to 50% globally. These advancements continue to offer new hope for those facing infertility and have significantly improved success rates, reaching approximately 70%. But what exactly is 4th generation IVF? And why is it revolutionizing the ART Fields?

1. 3rd Generation vs 4th Generation IVF Comparison

The key component for 4th generation IVF is the usage of the AI Time-Lapse Embryo Incubator system, which provides a stable environment for culturing while also capturing the embryo’s morphology process automatically. This can detect details of the developmental phase and, combined with an AI system, improve the data analysis, giving accurate scores to each embryo based on its implantation potential, which will significantly improve success rates. Another key component is PGT-A (Preimplantation Genetic Testing for Aneuploidies), which screens embryos for chromosomal abnormalities before implantation, which increases the chances of a healthy pregnancy.

Assessment Criteria	Singapore	Malaysia	Taiwan(NUWA)
Generation	3rd Gen IVF	3rd Gen IVF	4th Gen IVF
PGT-A Testing Availability	Not Available	Limited Access / Extra Cost	Already Included
Embryo Biopsy	Not Mentioned	Not Mentioned	Already Included
AI Time-Lapse Embryo Incubator	Extra Cost per Embryo	Extra Cost per Embryo	Already Included
Pregnancy Success Rates	Ranked 6th Globally	Ranked 6th Globally	Ranked 2nd Globally (Only 2nd to USA)

While there are many reputable IVF destinations in Asia, such as Singapore and Malaysia, these countries primarily offer 3rd-generation IVF due to limited access to 4th-generation technologies like PGT-A, which is available in Taiwan. For example, Singapore, a leader in the medical field, does not offer 4th-generation IVF because PGT-A is prohibited in Singapore’s private IVF clinics. As a result, many individuals travel to Taiwan for this advanced treatment.

Similarly, while Malaysia is also known for its IVF, some clinics lack access to AI time-lapse embryo technology and require testing at separate locations, which can be time-consuming and costly. This is why many opt to visit Taiwan for a comprehensive, all-in-one treatment, especially at NUWA Fertility, where each branch has its own lab, eliminating the need to transfer embryos and improve the success rate and safety of test tubes.

Different pregnancy success rates for age groups who have undergone IVF with and without PGT-A testing.

The pregnancy success rates for different age groups undergoing IVF with and without PGT-A testing show notable differences. For women aged 31-35, the success rate with PGT-A testing is 77%, compared to just 54% without the test. In the 36-40 age group, the success rate with PGT-A testing is 68%, significantly higher than the 34% success rate without it. For women aged 41-42, the success rate with PGT-A is 62%, a marked improvement over the 24% success rate without testing. These figures highlight the positive impact of PGT-A testing on IVF outcomes, particularly as age increases.

2. How does 4th generation IVF increase the chances of successful IVF pregnancy? (H2)

（1）Advantages of PGT-A Testing

Preimplantation Genetic Testing for Aneuploidies (PGT-A), formerly known as PGS, is a screening procedure used during IVF to detect chromosomal abnormalities in embryos before transfer, PGT-A provides a more accurate assessment of an embryo’s chromosomal status.

This advanced testing helps prevent the transfer of abnormal embryos, enhances pregnancy success rates, lowers miscarriage risks, and is particularly beneficial for individuals with recurrent pregnancy loss or a family history of chromosomal disorders.

（2）Advantages of AI Embryo Time-lapse Technology

Time-lapse imaging (TLI) technology enhances embryo evaluation and selection by providing detailed insights into embryonic development, allowing for an accurate point system and grading. This helps identify the best embryos for transfer, improving the chances of success.

Additionally, this technology eliminates the need for human contact during the process, reducing the observational time restrictions and additional stress to embryos during culture and assessment resulting in lower risk of embryo damage. It also has the ability to track various parameters over time allowing for better predictions of embryo implantation.

As research continues, TLI’s predictive power could significantly improve IVF success rates by selecting embryos with higher development potential, ultimately improving pregnancy outcomes.

（3）Why Choose NUWA for 4th Generation IVF?

At NUWA, we offer customizable IVF treatment, ensuring that every patient receives a plan tailored to their condition and budget. While we provide cutting-edge 4th Generation IVF, the final decisions are entirely up to you—The doctor will guide patients through their treatment plan, offering personalized medical advice tailored to their specific needs.

Beyond advanced technology, we prioritize a seamless experience with no language barriers, ensuring clear communication for international patients. Our team is dedicated to caring service, providing compassionate support throughout your journey.

With high-quality medical resources and advanced laboratories at every branch, reducing risks and enhancing success rates. At NUWA, you receive world-class fertility care, designed entirely around you.

3. NUWA Success Story

A couple from Australia knew their journey to starting a family wouldn’t be like everyone else’s. While some conceive effortlessly, others endure multiple rounds of IVF without success. Determined to give themselves the best possible chance, they began searching for a clinic that combined medical expertise with genuine care.

Their search led them to NUWA Fertility Center. It was a carefully considered decision—and one they would later look back on with gratitude. As the husband primarily speaks English, he was especially thankful that the doctors took the time to clearly explain everything in a language he understood. It not only helped him feel more confident and informed but also relieved his wife of the constant pressure to translate—something that meant the world to both of them.

After months of effort, hope, and waiting, they are now proud parents to a beautiful baby girl. The wife describes the result as magical, even miraculous. The husband calls it science at its finest. But on one thing they both agree: they would not be holding their daughter today without NUWA.

IVF is far from easy; it takes a toll emotionally, physically, and in unexpected ways. But throughout the process, every bit of support counted. They are very grateful and even writing a comment on Google review stating:

"To everyone at NUWA—the compassionate staff, the skilled doctors and nurses, and everyone behind the scenes—thank you. Your professionalism, kindness, and world-class care made this journey possible. From the spotless waiting areas to the thoughtful touches like snacks and water, everything reflected your dedication. We’ll never forget it. From our hearts, and on behalf of our little daughter we want to say thank you."

4. NUWA’s Assisted Reproductive Technology Seminar in Singapore！

The First Ever NUWA Seminar in Orchard, Singapore!

NUWA Fertility Center is a leading IVF center in Asia and a large clinic chain in Taiwan, with nearly 10,000 successful medical experiences. As the institution in Taiwan equipped with 8 AI embryo time-lapse incubators, our expert team combines advanced technology and world-class care to ensure the highest quality laboratory operations. We are now bringing our exceptional services to Singapore!

Event Details:

- Date: May 4, 2025 （Sunday）

- Time: 13:00 - 17:00 (Check-In at 12:30)

- Venue: 5F, Voco Orchard, Singapore - 581 Orchard Rd, Singapore 238883

- Attending Physicians: Dr. Meng-Shun Shen, Dr. Po-Wei Chu

Contents of the seminar:

🔸 NUWA's 4th-Gen IVF: The Secret to Our Outstanding Success Rate (With PGT-A (PGS) & AI Time-lapse Technology)

🔸 Advanced Fertility Preservation: Egg and Embryo Freezing

🔸 Personalized Medical Process: Timeline and Duration of Your Selected Treatments

🔸 Exclusive 1-on-1 Consultation with Our Expert Doctors – Free on-site!

A confirmation letter will be sent to your Email or NUWA Fertility Center's WhatsApp（+886 965 606 851）, and we'll reserve your seat for you. Enjoy an informative seminar, exclusive deals, and free consultations with experts in the fertility medical field. We look forward to seeing you there!

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