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A Mom of Two: Pregnant at 41
Dr. Huai Ling Wang
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Facing Age 40 with an AMH Below 0.2: Will You Still Have the Confidence to Continue the Challenge?
When you’re 40 and have only one embryo, do you still have the courage to continue culturing it to day five, even facing the harsh test of PGS?
Low AMH Below 0.2, Successfully Gives Birth to a Healthy Baby
Many people, including doctors, often fear that with a low number of eggs, the longer the timeline, the less likely it is to culture a viable blastocyst and lose the chance for implantation. They worry that after finally culturing to day five, the embryo may fail the PGS test. Thus, they may choose to implant immediately after fertilization, hoping the uterine environment is more suitable for the embryo's growth.
Miss W, now 41 years old, had only one embryo. What gave her the courage to continue observing it and even choose to undergo PGS?
Four years ago, at 37, her ovarian function wasn’t great, and her AMH was already below 1. After being married for five years without good news, she opted for IVF. Due to her poor ovarian function, she adopted a strategy of egg collection, undergoing three retrievals, collecting 11 eggs, and creating 9 embryos, eventually resulting in 4 blastocysts. One of those blastocysts underwent PGS, and luckily, this normal embryo allowed her to successfully conceive her first baby boy.
Successfully Gives Birth to Second Baby Through Blastocyst Culturing and PGS
After two years, she began implanting the remaining three embryos. However, since they hadn’t undergone PGS, the implantation failed her second child.
Now at 41, her ovarian function had worsened compared to three years ago. This time, she only retrieved two eggs, resulting in just one embryo.
Understanding the high probability of chromosomal abnormalities at this stage, she realized that even if implantation succeeded, she could face risks of miscarriage, requiring additional time to recover. For her, the time cost was substantial! Thus, she chose a direct approach, challenging herself to culture the blastocyst and hope for PGS.
Fortunately, with the help of fate and the meticulous care of the embryo medical team, this single embryo successfully reached day five and passed the PGS test, confirming it as a normal embryo! After the embryo was implanted, Dr. Han Jianming assisted in addressing uterine polyps, leading to a successful pregnancy and allowing her to graduate and continue her journey toward happiness! Believing in this unique opportunity can indeed bring good fortune!